As a chervo jacke herren main regulator of melanocyte development and an key melanoma oncogene, microphthalmia-associated transcription factor (MITF) is one of the proteins in the basic helix-loop-helix zipper (bHLHZip) transcription factor family.The study on the detailed binding specificity of the MITF/DNA complex has been a challenge.MITF-DNA in
Silk is obtained mostly from oval cocoons.In this paper, the flat cocoons were obtained by changing the silking environment of Bombyx mori silkworms.Then the appropriate method was used to reel the flat cocoons.The structure, thermal and mechanical properties of flat cocoon silk (FCS) after silk reeling and degumming were studied.The experimental r
Cell fate choices are tightly controlled by the interplay between intrinsic and extrinsic signals, and gene regulatory networks.In Saccharomyces cerevisiae, the decision to enter into gametogenesis or sporulation is dictated by mating type and nutrient availability.These signals regulate the expression of the master regulator of gametogenesis, IME1